A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits

Objectives: The overarching goal was to employ statistical colocalization as a means to elucidate the causal genes and underlying mechanisms implicated in complex diseases. This objective involved bridging the gap between genome-wide association studies (GWAS) and biological interpretations by prioritizing variants likely to be causal, assessing genetic overlap among related traits, and discerning the presence… Continue reading A fast and efficient colocalization algorithm for identifying shared genetic risk factors across multiple traits