View the full research paper on Nature Communications Objectives: This study aimed to explore how gene-environment interactions (GEIs) affect protein levels in the human body, specifically within the plasma proteome. The focus was on identifying variance quantitative trait loci (vQTLs) that signal these interactions, and understanding how genetic and environmental factors together influence protein expression.… Continue reading Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank
Tag: UK Biobank
Blood protein levels predict leading incident morbidities and mortality in the UK Biobank
Objective: The overarching aim of this study was to explore the intricate relationship between the circulating proteome and age-related diseases and mortality using data from the UK Biobank. By analyzing blood data from 47,600 individuals over 16 years and linking it with electronic health records, our primary objective was to elucidate the associations between 1,468… Continue reading Blood protein levels predict leading incident morbidities and mortality in the UK Biobank