View the full research paper on Nature Communications Objectives: This study aimed to explore how gene-environment interactions (GEIs) affect protein levels in the human body, specifically within the plasma proteome. The focus was on identifying variance quantitative trait loci (vQTLs) that signal these interactions, and understanding how genetic and environmental factors together influence protein expression.… Continue reading Systematic discovery of gene-environment interactions underlying the human plasma proteome in UK Biobank
Tag: AI
Blood protein assessment of leading incident diseases and mortality in the UK Biobank
Objectives: The primary goal was to identify genetic variants linked to Alzheimer’s disease (AD) using advanced genomic techniques. The study aimed to enhance understanding of the genetic underpinnings of AD by employing sophisticated methods to analyse large-scale genomic data. Key objectives included pinpointing novel genetic variants associated with AD, elucidating their functional roles, and exploring… Continue reading Blood protein assessment of leading incident diseases and mortality in the UK Biobank